Office of Biotechnology Activities    National Institutes of Health - Office of Science Policy   NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules   Effective March 5, 2013     For the full text of NIH Guidelines (HTML)     For the full text of NIH Guidelines     Printer-Friendly version of NIH Guidelines         Federal Register notice dated September 5, 2012, announcing amendments to the NIH Guidelines effective March 5, 2012     FAQs for NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (April 2013)     NIH Public Consultation on Synthetic Nucleic Acids and the NIH Guidelines         Effective February 21, 2013     In response to recent publications examining the genetic changes that may enable currently circulating strains of highly pathogenic avian influenza H5N1 strains within the Goose/Guangdong/95-like lineage (HPAI H5N1) to transmit among mammals by respiratory droplets, the NIH Guidelines have been amended to address biocontainment for such research.     Mammalian-Transmissible HPAI H5N1 Amendments - Effective Immediately     Federal Register         Additional background information about the NIH Guidelines is available including:     Links to Federal Register Notices Regarding the Guidelines since 1994

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